Wednesday, May 19, 2010
Thursday, May 6, 2010
UPDATE 1-US lawmakers seek data from FDA on J&J recall
U.S. lawmakers on Thursday requested information from regulators about Johnson & Johnson's (JNJ.N) recall of Children's Tylenol and other over-the-counter pediatric medicines, saying the company's repeated recalls "point to a major problem" with production.
The U.S. House of Representatives Committee on Oversight and Government Reform has opened an investigation after J&J recalled 40 widely used children's pain and allergy medications, saying some may have a higher concentration of their active ingredients, while others may be contaminated.
In a damning FDA report issued on Tuesday, inspectors said they found thick dust, grime and contaminated ingredients at the J&J plant that produces Children's Tylenol and dozens of other products recalled last week. [ID:nN04255618]
J&J has now had four recalls in the past year of over-the-counter medicines.
"Taken together, these recalls point to a major problem in the production of McNeil products," Committee Chairman Edolphus Towns, a New York Democrat, and the panel's ranking Republican, Darrell Issa of California, said in a release, referring to J&J's consumer healthcare unit.
"Given McNeil's questionable track record and consecutive recalls, we need to understand what prior actions the (Food and Drug Administration) took to address McNeil's quality control problems and what events led the FDA to its April 2010 inspection of McNeil's Fort Washington plant."
The committee requested information and records in a letter to FDA Commissioner Margaret Hamburg, which was included in its press release on Thursday.
The committee is seeking to clarify the timing of the events that spurred the recall in order to understand J&J's and FDA's response, according to the release.
Among other questions, the letter asks Hamburg to identify the bacteria found in raw materials at McNeil's Fort Washington, Pennsylvania, plant, where the pediatric products in question were made.
The FDA will promptly review the committee's letter and information request, a spokesman said.
"We will certainly respond to those inquiries and fully cooperate with the committee's investigation," the agency spokesman said.
J&J's McNeil unit declined to comment.
In a release on Wednesday, the lawmakers said they were questioning the adequacy of the FDA's inspection procedures and whether J&J's McNeil unit failed to investigate consumer complaints that could have identified the contamination problems.
The committee said it expects to hold a hearing "in the coming weeks."it is your life
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The U.S. House of Representatives Committee on Oversight and Government Reform has opened an investigation after J&J recalled 40 widely used children's pain and allergy medications, saying some may have a higher concentration of their active ingredients, while others may be contaminated.
In a damning FDA report issued on Tuesday, inspectors said they found thick dust, grime and contaminated ingredients at the J&J plant that produces Children's Tylenol and dozens of other products recalled last week. [ID:nN04255618]
J&J has now had four recalls in the past year of over-the-counter medicines.
"Taken together, these recalls point to a major problem in the production of McNeil products," Committee Chairman Edolphus Towns, a New York Democrat, and the panel's ranking Republican, Darrell Issa of California, said in a release, referring to J&J's consumer healthcare unit.
"Given McNeil's questionable track record and consecutive recalls, we need to understand what prior actions the (Food and Drug Administration) took to address McNeil's quality control problems and what events led the FDA to its April 2010 inspection of McNeil's Fort Washington plant."
The committee requested information and records in a letter to FDA Commissioner Margaret Hamburg, which was included in its press release on Thursday.
The committee is seeking to clarify the timing of the events that spurred the recall in order to understand J&J's and FDA's response, according to the release.
Among other questions, the letter asks Hamburg to identify the bacteria found in raw materials at McNeil's Fort Washington, Pennsylvania, plant, where the pediatric products in question were made.
The FDA will promptly review the committee's letter and information request, a spokesman said.
"We will certainly respond to those inquiries and fully cooperate with the committee's investigation," the agency spokesman said.
J&J's McNeil unit declined to comment.
In a release on Wednesday, the lawmakers said they were questioning the adequacy of the FDA's inspection procedures and whether J&J's McNeil unit failed to investigate consumer complaints that could have identified the contamination problems.
The committee said it expects to hold a hearing "in the coming weeks."it is your life
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Words to Live by
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Dreams about taking exam, being naked -- what they mean
You're in a classroom and the teacher puts an exam face down on your desk. You pick it up and can't really make out what's on it; it's blurry, or it's in another language, or it's in a subject you didn't study.
You feel like you're going to fail, even though it's been years since you've actually been in school.
People commonly relive this scenario in their dreams, even decades after their last graduation. While many high school, college and graduate school students are cramming for real exams this week, you may dream about it if you have anxiety about being judged, or if you're in a situation you don't know how to handle, experts say.
Dreams are "an extremely rich source of practical advice, and other alternatives about what we're doing in our lives," said Deirdre Barrett, Harvard psychologist and author of "The Committee of Sleep" and "Trauma and Dreams." "They're just coming from such a different part of ourselves that they're a very good supplement to our waking, rational thinking."
The dreaming brain
Scientists know about as much about the dreaming brain as they do the waking brain -- in other words, there's still a lot to learn about how the brain creates the dreaming consciousness and wakeful consciousness, said William Dement, leading sleep researcher at Stanford University.
Dreaming happens during the REM (rapid eye movement) stage of sleep. In a typical sleep cycle, there are 68 minutes of non-REM sleep and 22 minutes of REM sleep. An eigt-hour night of sleep will include about six REM periods, during which multiple dreams can occur.
The body is temporarily paralyzed during REM sleep. But in a rare condition called REM behavior disorder, people act out what they are doing in their dreams, be it talking or running into a wall.
You are conscious in your dreams in basically the same way you are conscious in real life, but you don't remember dreams as well because memory processing is down, Dement said. The continuity of real life experiences helps you distinguish waking life from the dream world. For example, you don't magically reappear in a different setting in the real world, whereas it might appear that way in a single night of dreaming.
"In some ways, it's very good we don't remember our dreams very well," he said. "You'd constantly be saying, 'Did that happen, or was it a dream?' "
Inside your dreams
The symbols and events in dreams can mean many different things to different people, Barrett said. A dog might signal unconditional love to someone who has positive feelngs toward canines; someone else with a fear of dogs might dream about them as a reflection of trauma.
But themes such as the "test you're not prepared for" do tend to have common meanings for people. A similar dream occurs for people who had experience in acting as a child: They dream that they forgot there was an audition that day, or that they get to an audition and it's in a garbled language, or they studied the wrong script -- they're being judged, or don't know what to do in this situation. People also commonly have dreams in which they are naked in public, associated with feeling exposed or ashamed. This could signal that the dreamer feels socially inadequate in some way, Barrett said
These are "psychological dreams" that are telling you that you should figure out where in life you are having a block, or how you should handle your difficult problem, said Dr. Judith Orloff, author of "Second Sight" and assistant clinical professor of psychiatry at the University of California, Los Angeles.
Nightmares can shed light into the dark areas of people's lives, Orloff said. They confront people with what they are most afraid of, and can be used to work through underlying problems.
Orloff had one patient who repeatedly dreamed she was being chased on a cliff by an "evil pursuer" who was going to hurt her. The patient and psychologist figured out that the pursuer represented the woman's abusive father. After working through it, the nightmare did not repeat.
Letting your dreams help you
If you want further insight into a difficult decision, consider asking a question before you go to bed, and then seeing what happens in your dream, Orloff said. Get a dream journal and write down the question at night; in the morning, without getting out of bed, write down everything you remember.
One patient of Orloff's had to make a difficult decision about whether to take a new job, and dreamed that she was in the new position but had a negative experience. This helped her realize that she did not get along with the boss, and she decided against the job, Orloff said.
Dement said he is somewhat skeptical about putting a lot of weight in dream interpretation. Dreams are often hard to remember, the associations in them can mean multiple things, and you shouldn't stress if you can't recall details, he said. It can be quite difficult to summon a memorable dream to answer a question in the way that Orloff recommends, he said.
But Dement agreed that dreams can help with major life events. He himself once had a life-changing dream: He had been trying to quit smoking, but simply could not, and dreamed that he had coughed up pink sputum indicative of cancer.
"I felt just utter complete despair -- I would never see my children grow up, I did it to myself because I didn't quit, I hadn't put enough aside to take care of my family," he said. "Then I woke up. I never smoked another cigarette."
Important discoveries have also emerged as a consequence of dreams. Otto Loewi, a German pharmacologist, is said to have dreamed about an experiment to show that the transmission of nerve impulses is chemical, not electrical. The experiment worked in real life, and Loewi went on to the Nobel Prize in medicine in 1936.
Some artists and musicians use their dreams for inspiration. The writer Robert Louis Stevenson drew on his dreams for "The Strange Case of Dr. Jekyll and Mr. Hyde."
The bottom line: Trust your waking, logical thinking, but don't ignore what your intuitive, feeling-based, visual side might have to say about difficult decisions through dreams, Barrett said.
"It can be very important to look to our dreams on anything that we're kind of stuck on in our waking lives, because the dream thoughts are likely to be so different, and they may really think outside the box and come up with an answer that we haven't awake," Barrett said. Who Am I?
Wake up your life
Just Listen
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The Matrixhttp://www.twilightteens.com/forum
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You feel like you're going to fail, even though it's been years since you've actually been in school.
People commonly relive this scenario in their dreams, even decades after their last graduation. While many high school, college and graduate school students are cramming for real exams this week, you may dream about it if you have anxiety about being judged, or if you're in a situation you don't know how to handle, experts say.
Dreams are "an extremely rich source of practical advice, and other alternatives about what we're doing in our lives," said Deirdre Barrett, Harvard psychologist and author of "The Committee of Sleep" and "Trauma and Dreams." "They're just coming from such a different part of ourselves that they're a very good supplement to our waking, rational thinking."
The dreaming brain
Scientists know about as much about the dreaming brain as they do the waking brain -- in other words, there's still a lot to learn about how the brain creates the dreaming consciousness and wakeful consciousness, said William Dement, leading sleep researcher at Stanford University.
Dreaming happens during the REM (rapid eye movement) stage of sleep. In a typical sleep cycle, there are 68 minutes of non-REM sleep and 22 minutes of REM sleep. An eigt-hour night of sleep will include about six REM periods, during which multiple dreams can occur.
The body is temporarily paralyzed during REM sleep. But in a rare condition called REM behavior disorder, people act out what they are doing in their dreams, be it talking or running into a wall.
You are conscious in your dreams in basically the same way you are conscious in real life, but you don't remember dreams as well because memory processing is down, Dement said. The continuity of real life experiences helps you distinguish waking life from the dream world. For example, you don't magically reappear in a different setting in the real world, whereas it might appear that way in a single night of dreaming.
"In some ways, it's very good we don't remember our dreams very well," he said. "You'd constantly be saying, 'Did that happen, or was it a dream?' "
Inside your dreams
The symbols and events in dreams can mean many different things to different people, Barrett said. A dog might signal unconditional love to someone who has positive feelngs toward canines; someone else with a fear of dogs might dream about them as a reflection of trauma.
But themes such as the "test you're not prepared for" do tend to have common meanings for people. A similar dream occurs for people who had experience in acting as a child: They dream that they forgot there was an audition that day, or that they get to an audition and it's in a garbled language, or they studied the wrong script -- they're being judged, or don't know what to do in this situation. People also commonly have dreams in which they are naked in public, associated with feeling exposed or ashamed. This could signal that the dreamer feels socially inadequate in some way, Barrett said
These are "psychological dreams" that are telling you that you should figure out where in life you are having a block, or how you should handle your difficult problem, said Dr. Judith Orloff, author of "Second Sight" and assistant clinical professor of psychiatry at the University of California, Los Angeles.
Nightmares can shed light into the dark areas of people's lives, Orloff said. They confront people with what they are most afraid of, and can be used to work through underlying problems.
Orloff had one patient who repeatedly dreamed she was being chased on a cliff by an "evil pursuer" who was going to hurt her. The patient and psychologist figured out that the pursuer represented the woman's abusive father. After working through it, the nightmare did not repeat.
Letting your dreams help you
If you want further insight into a difficult decision, consider asking a question before you go to bed, and then seeing what happens in your dream, Orloff said. Get a dream journal and write down the question at night; in the morning, without getting out of bed, write down everything you remember.
One patient of Orloff's had to make a difficult decision about whether to take a new job, and dreamed that she was in the new position but had a negative experience. This helped her realize that she did not get along with the boss, and she decided against the job, Orloff said.
Dement said he is somewhat skeptical about putting a lot of weight in dream interpretation. Dreams are often hard to remember, the associations in them can mean multiple things, and you shouldn't stress if you can't recall details, he said. It can be quite difficult to summon a memorable dream to answer a question in the way that Orloff recommends, he said.
But Dement agreed that dreams can help with major life events. He himself once had a life-changing dream: He had been trying to quit smoking, but simply could not, and dreamed that he had coughed up pink sputum indicative of cancer.
"I felt just utter complete despair -- I would never see my children grow up, I did it to myself because I didn't quit, I hadn't put enough aside to take care of my family," he said. "Then I woke up. I never smoked another cigarette."
Important discoveries have also emerged as a consequence of dreams. Otto Loewi, a German pharmacologist, is said to have dreamed about an experiment to show that the transmission of nerve impulses is chemical, not electrical. The experiment worked in real life, and Loewi went on to the Nobel Prize in medicine in 1936.
Some artists and musicians use their dreams for inspiration. The writer Robert Louis Stevenson drew on his dreams for "The Strange Case of Dr. Jekyll and Mr. Hyde."
The bottom line: Trust your waking, logical thinking, but don't ignore what your intuitive, feeling-based, visual side might have to say about difficult decisions through dreams, Barrett said.
"It can be very important to look to our dreams on anything that we're kind of stuck on in our waking lives, because the dream thoughts are likely to be so different, and they may really think outside the box and come up with an answer that we haven't awake," Barrett said. Who Am I?
Wake up your life
Just Listen
The Matrix Revolutions
The Matrixhttp://www.twilightteens.com/forum
http://focusclub.nl/forum
http://www.3d-heliforum.de
http://www.masterful-magazine.com/forum
http://www.passfans.com
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Sunday, March 14, 2010
Wireless Sensor Networks
Wireless Sensor Networks (WSN) is a large number of distributed, small, specifications and functions of different sensor nodes, through its own sensing, computing and communications capability posed by the network system. It can be integrated dynamic signal acquisition, processing and transmission of information and can automatically adapt to environmental changes, in the case of unattended task independently.In this paper, with the topic of "Research and development for Smart IP wireless sensor control of the ARM-side ", after detailed research and feasibility studies, on the basis of the current in-depth study of the popular theory ,this paper produces a new way to realize it. The use of embedded technology in the ARM processor platform design and development of a wireless embedded sensor, the major work done including:First, on the background of wireless sensor networks, the development of the status, meaning and content of the study, and then combined with the embedded IP sensor theory, discusses the working principle of their model and get ready for actual system design.
Sunday, March 7, 2010
Joystar Int’l Development Ltd
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